您好，欢迎来到虫洞时空！
请登录
[买家]
[卖家]
|
免费注册
买家注册
卖家注册
| 品牌 | CST | |
| 基础属性 | 生产企业 | |
| cas号 | ||
| 规格 | 20 µl | |
| 储存条件 | ||
| 纯度 | ||
| 密度 |
| REACTIVITY | H M R Mk |
| SENSITIVITY | Endogenous |
| MW (kDa) | 17, 19 |
| Source/Isotype | Rabbit IgG |
100 µl
100 µl
100 µl
Product Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Simple Western™ | 1:10 - 1:50 |
| Immunoprecipitation | 1:50 |
| Immunohistochemistry (Paraffin) | 1:2000 |
| Immunofluorescence (Immunocytochemistry) | 1:400 - 1:1600 |
| Flow Cytometry (Fixed/Permeabilized) | 1:6400 |
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
For a carrier free (BSA and azide free) version of this product see product #94530.
Cleaved Caspase-3 (Asp175) (5A1E) Rabbit mAb detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175. This antibody does not recognize full-length caspase-3 or other cleaved caspases. Non-specific labeling may be observed by immunofluorescence in specific sub-types of healthy cells in fixed-frozen tissues (e.g. pancreatic alpha-cells). Cytoplasmic background may be observed in human and monkey samples.
Human, Mouse, Rat, Monkey
Bovine, Dog, Pig
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to amino-terminal residues adjacent to Asp175 of human caspase-3.
Caspase-3 (CPP-32, Apopain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires the aspartic acid residue at the P1 position (2).
虫洞平台上的所有商品信息、客户评价、商品咨询、网友讨论等内容，是虫洞时空重要的经营资源，未经许可，禁止非法转载使用。
注：本站商品信息均来自于合作方，其真实性、准确性和合法性由信息拥有者（合作方）负责。本站不提供任何保证，并不承担任何法律责任。
批发价/零售价/专属价：均为商品的销售价，不同性质的单位所看到的价格会有所不同，是您最终决定是否购买商品的依据。 划线价：商品展示的划横线价格为参考价，并非原价，该价格可能是品牌标价或由品牌供应商提供的零售价（如厂商指导价、建议零售价等） 或该商品在虫洞平台上曾经展示过的销售价；由于地区、时间的差异性和市场行情波动，品牌专柜标价、商品吊牌价等可能会与您购物时展示的不一致，该价格仅供您参考。
异常问题：商品的具体售价以订单结算页价格为准；如您发现商品售价或促销信息有异常，建议购买前先联系卖家咨询。
北京虫洞时空于2021年10月成立，为进一步提升实验室供应链效率， 解决实验室在采购中存在的选货、价格、物流和结算难等问题，提升实验室服务的互联网化水平，公司致力于成为中国领先的专业实验室第三方电商平台。
