您好,欢迎来到虫洞时空! 请登录 [买家] [卖家] | 免费注册 买家注册
卖家注册

首页> 生物试剂> 抗原与抗体> 一抗> 杭州达真生物技术有限公司> 商品详情
收藏商品 查看百科

ILT4 Polyclonal Antibody  

登录可见价格

货号YT5595

品牌ImmunoWay

品牌类型无授权品牌

货期2天

规格
数量

-+

杭州达真生物技术有限公司

联系人:登录可见

联系方式:登录可见

立即登录

在线客服

登录后可查看详细客服信息

立即登录
  • 详细信息
品牌 ImmunoWay
基础属性 生产企业
cas号
规格 40ul
储存条件 -20
纯度
密度
  • 靶点:
  • CD85d
  • 简介:
  • >>Osteoclast differentiation;>>B cell receptor signaling pathway
  • 基因名称:
  • LILRB2
  • 蛋白名称:
  • Leukocyte immunoglobulin-like receptor subfamily B member 2
  • Human Swiss Prot No:
  • Q8N423
  • 免疫原:
  • The antiserum was produced against synthesized peptide derived from the Internal region of human LILRB2. AA range:121-170
  • 特异性:
  • CD85d Polyclonal Antibody detects endogenous levels of CD85d protein.
  • 组成:
  • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源:
  • Polyclonal, Rabbit,IgG
  • 稀释:
  • WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺:
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度:
  • 1 mg/ml
  • 储存:
  • -15°C to -25°C/1 year(Do not lower than -25°C)
  • 其他名称:
  • LILRB2;ILT4;LIR2;MIR10;Leukocyte immunoglobulin-like receptor subfamily B member 2;LIR-2;Leukocyte immunoglobulin-like receptor 2;CD85 antigen-like family member D;Immunoglobulin-like transcript 4;ILT-4;Monocyte/macrophage immunoglobulin-like receptor 10;MIR-10;CD85d
  • 实测条带:
  • 66kD
  • 背景:
  • This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
  • 功能:
  • domain:Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.,PTM:Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds PTPN6 when phosphorylated. Binds FCGR1A.,tissue specificity:Expressed on monocytes and B-cells, a
  • 细胞定位:
  • Cell membrane ; Single-pass type I membrane protein.
  • 组织表达:
  • Expressed in monocytes and at lower levels in myeloid and plasmacytoid dendritic cells. Expressed in tolerogenic IL10-producing dendritic cells (PubMed:20448110). Expressed in myeloid-derived suppressor cells during pregnancy (PubMed:27859042). Detected at low levels in natural killer (NK) cells. Expressed in B cells.

权利声明:

虫洞平台上的所有商品信息、客户评价、商品咨询、网友讨论等内容,是虫洞时空重要的经营资源,未经许可,禁止非法转载使用。
注:本站商品信息均来自于合作方,其真实性、准确性和合法性由信息拥有者(合作方)负责。本站不提供任何保证,并不承担任何法律责任。

价格说明:

批发价/零售价/专属价:均为商品的销售价,不同性质的单位所看到的价格会有所不同,是您最终决定是否购买商品的依据。 划线价:商品展示的划横线价格为参考价,并非原价,该价格可能是品牌标价或由品牌供应商提供的零售价(如厂商指导价、建议零售价等) 或该商品在虫洞平台上曾经展示过的销售价;由于地区、时间的差异性和市场行情波动,品牌专柜标价、商品吊牌价等可能会与您购物时展示的不一致,该价格仅供您参考。

异常问题:商品的具体售价以订单结算页价格为准;如您发现商品售价或促销信息有异常,建议购买前先联系卖家咨询。

客户服务

400-070-8283

周一至周五  8:30-18:30 联系客服

何为虫洞

北京虫洞时空于2021年10月成立,为进一步提升实验室供应链效率, 解决实验室在采购中存在的选货、价格、物流和结算难等问题,提升实验室服务的互联网化水平,公司致力于成为中国领先的专业实验室第三方电商平台。

扫码关注公众号

促销

海量货品低价团

正品

正品保障放心购

售后

售后无忧全部保

北京虫洞时空信息科技有限公司CopyRight © 2021-2022, All Rights Reserved. 京ICP备16015371号 京公网安备11010802029253号