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| 品牌 | Proteintech | |
| 基础属性 | 生产企业 | |
| cas号 | ||
| 规格 | 100ug | |
| 储存条件 | 4 | |
| 纯度 | ||
| 密度 |
| Positive FC detected in | rat splenocytes |
| APPLICATION | DILUTION |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
APC-65180 targets CD8a in FC applications and shows reactivity with rat samples.
| Tested Applications | FC |
| Tested Reactivity | Rat |
| Immunogen | N/A 种属同源性预测 |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | CD8a molecule |
| Synonyms | Cd8a, CD8a molecule |
| GenBank accession number | BC088126 |
| Gene symbol | Cd8a |
| Uniprot | P07725 |
| Gene ID (NCBI) | 24930 |
| Conjugate | APC Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 650 nm / 660 nm |
| Form | Liquid |
| Purification Method | Purified by protein-A affinity chromatography |
| Storage Buffer | PBS with 0.1% sodium azide and 0.5% BSA. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T-cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084).
| PRODUCT SPECIFIC PROTOCOLS | |
|---|---|
| FC protocol for APC CD8a antibody APC-65180 | Download protocol |
| STANDARD PROTOCOLS | |
|---|---|
| Click here to view our Standard Protocols |
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