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品牌 |
ZEN BIO |
基础属性 |
生产企业 |
成都正能生物技术有限责任公司 |
cas号 |
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规格 |
100T |
储存条件 |
—20°C |
纯度 |
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密度 |
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实验应用:FC,反应种属:Human,推荐稀释比:FC: 5μL per test for million cells or whole blood in 100 μL volume. ,别名:PTPRC,宿主来源:Mouse,背景介绍:Swiss-Prot Acc.P08575.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
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